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December 29, 2016 00:06

brain Sarcoma |Symptoms and treatment of sarcoma of the brain

brain sarcoma - a pathological disorder that affects the functioning of the whole organism.Consider the causes of the disease, symptoms, diagnostic methods, treatment methods and prognosis of survival.

sarcoma of the brain - this is a rare malignant disease, which occurs in 2% of all malignant tumors.Sarcoma occurs in patients of any age and is usually a knot.A characteristic feature of sarcoma of the brain - germination in the surrounding tissue, that is, recurrence and metastasis.The tumor penetrates and affects fatty tissue, muscles, tendons, nerves and all the areas where there is a connective tissue.Sarcoma is characterized by aggressive rapid growth.

Malignant tumor has blurred fuzzy boundaries aggressive in relation to the surrounding cells.The structure of the tumor is loose or tight junction, in some cases, the tumor has foci of calcification.

extracerebral and intracerebral brain tumors are divided into:

  • Meningosarkoma - the tumor originates from the meninges, which consist of a patho
    logically altered vessels.Capable of germination in other tissues and infiltrative growth, since it has no capsule.
  • Angioretikulosarkoma - comes from the walls of cerebral blood vessels.The tumor contains many capillaries, so it spreads through the bloodstream.
  • Fibrosarcoma - a tumor composed of fibrous layers and ligaments.Sarcoma progresses slowly, but is characterized by a steady increase of neurological symptoms.A typical symptom for this kind of cancer - chronic headaches, neurological and cerebral symptoms.

main sign of sarcoma - a persistent headaches that do not respond to treatment with drugs, anesthetics.The patient suffers from frequent dizziness can occur epileptic seizures, impaired coordination in space and walk.The tumor causes atrophy of the optic nerves, constant emotional and nervous disorders, and disorders of consciousness.

If brain sarcoma localized in the ventricles or clog their ducts, it causes disturbances of cerebrospinal fluid circulation.The patient intracranial pressure increases.If sarcoma localized in the nape of the neck area, the patient observed visual impairment, while tumors in the temples - hearing impaired.With the defeat of the frontal and parietal lobes there are violations of motor activity and mental abilities.If sarcoma originated by the pituitary gland, this leads to changes in the hormonal balance in the body.

To identify brain sarcoma, you must be examined by a neurologist.The doctor prescribe a CT scan and a number of other studies, which will help to identify the disease.For the final confirmation of the brain sarcomas, patients underwent punch biopsy.

Causes Kaposi brain

reasons sarcoma of the brain varied specification of the reasons that led to the appearance of the tumor is not possible.But there are several risk factors that can trigger the appearance of sarcoma.

  1. presence of genetic syndromes and hereditary diseases.Exposure to ionizing
  2. cure - brain tissue exposed to radiation, are predisposed to the appearance of malignant tumors.The risk of sarcoma maintained for 10 years from the time of exposure.
  3. herpes virus - this at first glance, not a dangerous disease that can cause Kaposi's sarcoma.
  4. Trauma and the impact of foreign bodies.
  5. lymphostasis Chronic upper limb after radical mastectomy.
  6. Immunosuppressive therapy, chemotherapy.

Risk factors for the appearance of the brain sarcoma include the patient's age, the effects of radiation and external chemicals.The most common sarcoma of the brain are affected older patients.Thus, the average age of patients with the disease - 57-60 years.But some kinds of brain sarcoma prevalent in pediatric patients.There are certain chemicals which increases the impact sarcoma - a dioxin and vinyl chloride.Whereas in the past a person has been exposed to radiation in the treatment of tumors, it only increases the risk of brain sarcoma.

Symptoms of brain sarcoma

Symptoms of cerebral sarcomas are very similar to symptoms of other tumor lesions.This is due to the fact that the sarcoma manifests itself progressive focal neurologic and cerebral symptoms.The patient feels a constant headaches, impaired vision and hearing, is a violation of the psyche and regular emotional disorders.Clinical manifestations correspond to the growth of sarcoma tumors, that is constantly growing.

Distinguish the following symptoms of Kaposi's brain:

  • Constant headaches, which can not be eliminated drugs.
  • Visual disturbances.
  • Nausea, vomiting, dizziness, impairment of consciousness.
  • Epileptic seizures, speech disorders and emotional disorders.

Symptoms depends on tumor localization, since the location of the sarcoma affects the structure of the brain, which are responsible for the execution of certain functions.

  • If the sarcoma is located in the interior of the ventricles of the brain, it can block the ducts and cause disturbances in the circulation of cerebrospinal fluid.This leads to an increase in intracranial pressure.
  • If sarcoma appeared in the occipital region, it leads to visual impairment.
  • If the tumor originated from the temporal lobes, then this is the reason of hearing loss.
  • When sarcoma in the parietal and frontal lobes, the negative impact effect on motor activity, sensory and intellectual abilities.

Sarcoma brain

brain sarcoma - a malignant tumor that affects the membranes and connective tissue.Brain tumors are very rare.Typically, sarcoma develops in a node that is positioned within the skull of the box.Neoplasm refers to vascular tumors and enveloped common in patients of any age.

All sarcoma affecting the brain are divided into intracerebral and extracerebral.Tumor structure can be loose or tight, i.e. node.Intracerebral tumors are characterized by rapid abnormal growth.A extracerebral sarcomas grow into the brain tissue, recur and metastasize quickly.In this type of injury, survival at 2 years was 30%.

Symptoms

Symptoms appear as a steady increase in neurological disorders.The most important sign of tumor - chronic headaches and dizziness.When sarcoma begins to grow, the patient is experiencing somatic symptoms.

Diagnosis For the diagnosis of sarcoma of the brain need to be examined by a neurologist and an ophthalmologist.The doctor will appoint CT with intravenous contrast and ultrasound.In addition to non-invasive methods of diagnosis, brain sarcoma determined by biopsy and cytology of cerebrospinal fluid.

Treatment Treatment depends on the location of the lesion, tumor size, patient age and manifested symptoms.Generally, treatment consists of total removal of the tumor.Surgical treatment is the most effective, but certain difficulties may arise during its implementation.Furthermore, brain surgery always carries a number of negative consequences that affect the future health of the patient.Today, for the treatment of malignant brain tumors use more modern methods.One of these methods is Stereotactic Radiosurgery and cyber knife.

sarcoma bone marrow

sarcoma of the bone marrow - a malignant lesion of hematopoietic bone marrow cells.The disease is called multiple myeloma, a disease-Rustitskogo Culler or sarcoma of the bone marrow.Pathology is most common in men aged 50-60 years old, although in rare cases, sarcoma affects younger patients.sarcoma of the bone marrow may be multiple and single hearth, that is solitary.Let us consider in more detail the two forms of the disease.

  1. Multiple sarcoma bone marrow

This pathological condition characterized by frequent bone pain and fractures.The patient suffers from anemia and renal disorders.Perhaps the reduction of hemoglobin and increase blood viscosity.Patients with multiple Kaposi's bone marrow often vein thrombosis and haemorrhage.Since bone is actively destroyed, in its composition of calcium ingested.calcium compounds in the form of stone and sand are deposited in the lung, kidney, stomach and other organs, causing infringement of their functioning.The patient suffers from frequent infections due to declining function of the immune system.

Multiple sarcoma of the bone marrow is divided into focal and widespread, ie poroticheskuyu form:

  • When focal sarcoma stagnant brain lesions have a clearly defined foci tissue destruction.Outbreaks have a round shape and may be of any size.The most common lesion found in the skull, sternum, ribs and pelvic bones.The tumor may be located on the long bones, such as the femur, causing increase in the affected part of the bone volume.
  • When poroticheskoy form of sarcoma is very difficult to identify specific tumor foci.The patient is observed symptoms of intoxication, there is a systemic osteoporosis (sharp pain in the body bends, jumping, coughing, sneezing, etc.).These symptoms are manifested clearly in the spinal column, as bones take the form of "fish vertebrae".There are pathological fractures of the vertebrae and ribs.
  1. Solitary sarcoma bone marrow

This form represents the early phase of bone marrow sarcoma, which affects other bones and acquires plural form in pathological development.Single sarcomas occur in young patients, and hit the ribs, pelvis, vertebrae.If the tumor is localized to the spine, it leads to pathological fractures.A single sarcoma causes pain on the lesions and swelling.The disease causes an increase in volume of the affected limbs due to swelling of the bone.

diagnosis of sarcoma of the bone marrow based on biopsy results, ie the study of tumor tissue sample from the hearth.When the unit sarcoma patients underwent surgical treatment, but with multiple sarcoma of the bone marrow - chemotherapy.In any case, both forms of the disease prognosis unfavorable.

Diagnostics brain Kaposi sarcoma

Diagnosis begins with a medical history of the brain and collect the patient's complaints of pain and disorders.The neurologist conducted a visual examination of the patient, neurological examination, and assigns a number of additional analyzes.The patient was sent for scans and to accurately confirm the diagnosis of biopsy and histological examination of the tumor tissue.Consider the basic methods of diagnosis of sarcoma.

  • Magnetic resonance imaging - the method allows to determine the exact location of sarcomas and identify metastases in the surrounding tissues and organs.Patients underwent X-rays of the chest to avoid metastasis to the lymph nodes and lungs.
  • Computed tomography - is stratified picture of brain tissue.For a more accurate diagnosis of CT and MRI with contrast is performed.In addition, patients underwent radionuclide bone scan system.
  • Ultrasound examination - to determine the displacement of the midline structures of the brain, which indicates the presence of the bulk process.

addition to the above methods of diagnosis, patients underwent lumbar puncture and cerebrospinal fluid taking on cytology.It is mandatory to angiography and needle biopsy, which confirmed the diagnosis - sarcoma of the brain.

sarcoma of the brain Treatment

sarcoma of the brain Treatment can be carried out by different methods.Patients performed surgery, treatment with radiation therapy and chemotherapy.The main feature of sarcomas and other malignancies - germination in the healthy tissue and the lack of clearly defined borders.Choice of treatment depends on the location of sarcoma, its size, the general condition of the patient and the relationship to the adjacent tissues.

  • surgery - involves the excision of the tumor.To access the sarcoma patients underwent craniotomy, that is opening the skull.Sarcoma impossible to remove completely, since it is unclear boundaries and grows into healthy tissue.Therefore, after the surgery, the patient waits for a course of radiation or chemotherapy to prevent recurrence of the disease and the complete destruction of malignant cells.The above methods can be used before the operation to reduce the size of the brain sarcoma.
  • Radiation therapy - carried out in the event that there is no possibility to carry out a surgical operation.It can be used in combination with chemotherapy and a course of several sessions.But this type of treatment has several side effects: nausea, headache, vomiting, increased fatigue.
  • Chemotherapy - is the standard treatment of malignant tumors.This type of treatment has a devastating effect on the cells of rapidly.But under the influence does not just sarcoma cells, but also healthy.Chemotherapy refers to the systematic method, as the impact on the entire body of the patient.As a result, the patient can have many side effects: nausea, vomiting, hair loss, diarrhea, fatigue, anemia, leukopenia, reduced the protective properties of the organism.
  • Radiosurgery - is used for the treatment of sarcoma of the brain, which can not operate.This method of treatment is non-invasive and is performed without anesthesia.Treatment is carried out by outpatient and after irradiation session, the patient can go home.
  • Stereotactic radiotherapy - technology involves the irradiation of the tumor with a thin beam of radiation from different angles.Treatment is monitored by a computer and magnetic resonance tomography.The method allows the direct radiation dose to only the tumor and not healthy tissue.The main advantage of this treatment - the absence of any contraindications.
  • CyberKnife - a modern technology which allows to treat tumors of any etiology and localization without invasive intervention.CyberKnife effective not only in treating tumor but also every metastasis localization and size.

Prevention brain Kaposi sarcoma

Prevention brain - a series of events that allow you to prevent the emergence of the disease.One of the factors contributing to the development of Kaposi's brain - this radiation.High doses of treatment, even if they are carried out for therapeutic purposes, may adversely affect the functioning of the whole body and cause brain sarcoma.

particular importance in the prevention of brain cancer is diagnosis, which must be periodically.Do not forget that sarcomas, as well as other cancers leads to certain death within a few months.Diagnosis of sarcoma is MRI and CT.These techniques can detect metastases smallest size.

  • If you are plagued by chronic headaches, keep a diary.Record all the details of when and where the pain began, the degree of their severity and duration.This will help the neurologist to diagnose your condition.
  • Pay special attention to anti-cancer diet.Eat a balanced way, giving preference to plant foods, which has anti-cancer effect.Vegetable fiber prevents contact of the body with carcinogens.
  • Avoid foods which contain nitrite (it smoked products and sausages).
  • Give up bad habits that increase the risk of malignancies, including sarcomas, brain and other pathological lesions.