Advices for Life

Investigation Of Hemostasis

December 01, 2016 00:08

Factor VII ( proconvertin )

Reference quantity (rate) of factor VII activity in plasma - 65-135%. Factor VII (proconvertin or Convertino) refers to the α2-globulins, and is synthesized in the liver, with the participation of vitamin K. In general, involved in the formation of tissue prothrombinase and the conversion of prothrombin to thrombin.Its half-life is 4-6 hours (the short half-life among the clotting factors)...

December 01, 2016 00:08

Factor XIII ( fibrinstabiliziruyuschy factor)

Reference quantity (rate) factor XIII activity in plasma - 100%. factor XIII (fibrin-stabilizing factor, fibrin stabilizing factor) refers to .beta.2-glycoproteins.Present in the vascular wall, platelets, red blood cells, kidney, lung, muscle, placenta.The plasma is in the form of a proenzyme, attached to fibrinogen.Factor XIII influenced by thrombin is converted into the active form XII...

October 07, 2016 23:03

Heparin in plasma

heparin activity in the plasma of normal - 0,24-0,6 kU / L. Heparin is a sulfated polysaccharide, is synthesized in mast cells, it does not cross the placenta.In a large number found in the liver and lungs.Turns anticoagulant antithrombin III in immediate action.Since fibrinogen, plasmin and adrenaline forms complexes having anticoagulant and fibrinolytic activity.At low concentrations, in...

October 07, 2016 23:03

The activated clotting time (ABC)

ABC OK - 80-120 p. Method for determination of activated clotting time (ABC) allows you to monitor and adjust the level of heparinization of the patient during the operation of artificial organs (heart-lung machine, artificial kidney, liver, hemosorbtion) count neutralizing dose of protamine sulfate and assess the completeness of neutralization of heparin.The big advantage of this method i...

October 07, 2016 23:03

Protein C

Reference quantity (rate) of protein C concentration in plasma - 70-130%. Protein C - vitamin K-dependent plasma glycoprotein.It is synthesized in the liver as an inactive proenzyme which, under the influence of thrombin-thrombomodulin complex is converted to the active form.Activated protein C - anticoagulant enzyme selectively inactivating factors Va and VIIIa by their hydrolysis in the ...

October 07, 2016 23:03

Protein S

Reference quantity (rate) of the total protein concentration in the blood plasma S - 60-140% free - 65-144%. Protein S - vitamin K-dependent plasma glycoprotein.Blood circulates in two forms: free (40%) and related to the complement component C4 (60%).They are in a dynamic equilibrium, but is active only free protein.Protein S - cofactor of protein C in the inactivation Va and VIIIa blood ...

October 06, 2016 23:03

Degradation products of fibrinogen / fibrin

Reference quantity (rate) PDP plasma concentrations - less than 10 mg / l. fibrinogen / fibrin degradation products are formed in the body during activation of the fibrinolysis system (plasmin interaction with fibrin and fibrinogen), which develops in response to the formation of intravascular fibrin.Degradation products of fibrinogen / fibrin have antitromboplastinovym, antithrombin and a...

October 06, 2016 23:03

D dimer

fragments are formed during decomposition of fibrin fibers - D-dimers.In determining using specific antisera the content of D-dimer can be seen to what extent in the study of blood fibrinolysis is expressed, but not fibrogenoliz. Reference values ​​(standard) concentration of D-dimer in the blood plasma - less than 0.25 g / ml (250 mg / L) or 0.5 ug equivalents of fibrinogen / ml (500 ug e...

October 06, 2016 23:03

coagulation |Decoding and rate of coagulation

Coagulation is a type of blood test.Spend it solely for the purpose of studying the clotting ability. This is a very topical issue today.After all, there are people who have a bad or blood clotting was not able to stop.All this can lead to death.However, cases with the presence of poor clotting rare, but, nevertheless, they are available. Coagulation - that kind of analysis? Many peopl...

October 06, 2016 23:03

The rate of coagulation

Norma coagulation is very important indicators.The fact that the analysis must meet certain acceptable figures.Any deviation indicates the presence of problems in humans.For more information on this issue can be found below. Norma coagulation in Table Normal coagulation indexes in the table includes the optimal performance.Thus, in the analysis as a result of a person gets some figures...