Advices for Life

Diagnosis Of Autoimmune Diseases

December 19, 2016 00:04

Anti-sperm antibodies in the blood

The normal serum sperm antibodies are absent. In men, sperm antibodies are formed as a result of an autoimmune reaction in the spermatogenic epithelium.Etiological factors contributing to the development of such a reaction include testicular trauma, bacterial and viral infections, surgery on the testicle (for example, after vasectomy sperm antibodies detect all men), in some cases, the cau...

December 19, 2016 00:04

Diagnosis of autoimmune diseases of the liver

Autoimmune mechanisms play an important role in the pathogenesis of a variety of liver diseases: chronic active hepatitis, chronic autoimmune hepatitis, primary biliary cirrhosis, primary sclerosing cholangitis, autoimmune cholangitis.An important feature of the impaired immune state of chronic active liver disease is the appearance of autoantibodies which react with different antigenic com...

December 19, 2016 00:04

Antimitochondrial antibodies in serum

Antimitochondrial antibody (AMA) by indirect immunofluorescence in the serum of normal is not defined;ELISA method using the normal values ​​- less than 20 IU / ml;20-25 IU / ml - frontier values. Antimitochondrial antibodies to antigens produced by the inner mitochondrial membrane.The antigen structure is a lipoprotein involved in the transport function of the membrane.Elevated total titr...

December 19, 2016 00:03

Antistreptolysin O in a blood serum

Reference values ​​antistreptolisin O (ASO) in serum: adults - less than 200 IU / mL, the children - up to 150 IU / mL. Infections caused by group A streptococcus, always evoke a specific immune response - a significant increase in antibody titer of at least one of the extracellular streptococcal antigens - streptolysin O, deoxyribonuclease B, hyaluronidase or nicotinamide adenindinukleoti...

December 19, 2016 00:03

C- reactive protein in the blood

Reference values ​​(normal) concentration of C-reactive protein (CRP) in the blood serum - less than 5 mg / l. C-reactive protein (CRP) - a protein consisting of 5 identical non-covalently associated with each other ring subunits.C-reactive protein in serum determined at various inflammatory and necrotic processes, is indicative of the acute phase of their flow.It got its name due to its a...

December 19, 2016 00:03

Diagnosis of antiphospholipid syndrome

Antiphospholipid syndrome (APS) refers to a group of rheumatic diseases and is characterized by the presence of autoantibodies to phospholipids.The reasons for the formation of autoantibodies is not exactly established.It is believed that the majority of human viruses tropic to the endothelium of blood vessels.Persistiruya therein viruses cause morphological and functional changes in the ce...

December 19, 2016 00:03

Antibodies to cardiolipin in the blood

Reference values ​​(normal) concentration in serum anticardiolipin antibodies: IgG - less than 19 IU / ml;IgA - less than 15 IU / ml;IgM - less than 10 IU / ml. anticardiolipin antibodies - antibodies to phospholipids (cardiolipin - di-phosphatidylglycerol) cell membranes, a leading indicator of the presence of antiphospholipid mindroma patients.Antibodies to cardiolipin - primary antibodi...

October 04, 2016 23:03

Laboratory diagnosis of autoimmune diseases of the kidneys

Glomerulonephritis is the most common form of primary renal disease, mainly affecting the glomeruli.Currently, the concept is well recognized immunological genesis of the disease. Glomerulonephritis - the result of inflammatory reactions to antigens leading to tissue damage.Although the specific antigens responsible for the development of glomerulonephritis, often unknown, they can be clas...

October 04, 2016 23:03

Antibodies to basement membrane in the glomerular blood

Normally antibodies to the basement membrane of the glomeruli in the serum missing. presence of antibodies to the glomerular basement membrane (anti-BMK) is most characteristic of patients with rapidly progressive glomerulonephritis (anti-BMK glomerulonephritis).All patients with anti-BMP glomerulonephritis can be divided into two groups: with renal disease and Goodpasture's disease (50%),...

October 04, 2016 23:03

Coombs

Normally antibodies to red blood cells are not available. Direct Coombs - antiglobulin test (agglutination in the gel reveals complete bivalent antibodies), which is determined using antibodies of class IgG and C3 complement component on the erythrocyte surface.Typically, antibodies elicited direct Coombs test, have broad specificity and is not associated with well established antigen.Posi...