Advices for Life

Diseases Of Children

December 20, 2016 00:03

Violation of methionine metabolism

number of defects in the metabolism of methionine leads to the accumulation of homocysteine ​​(and its dimer, homocysteine) with negative effects, including a tendency to thrombosis, dislocation of the lens, and disorders of the nervous system and skeleton. Homocysteine ​​- an intermediate metabolite of methionine;he or remetiliruetsya to form methionine, serine or connected to the cascade...

December 20, 2016 00:03

Defects in enzymes of ornithine cycle

Defects ornithine cycle enzymes are characterized by hyperammonemia in terms catabolism or protein load. Primary disorders of ornithine cycle include a lack of carbamoyl-phosphate synthase (CFS), ornithine transkarbamilazy deficiency (OTC) deficiency arginine suktsinatsintetazy (tsitrullinemiya) deficit argininosuktsinatliazy (arginine-succinic aciduria) and arginase deficiency (argininemi...

December 20, 2016 00:03

Violation of fructose metabolism

deficiency of enzymes involved in the metabolism of fructose, can be asymptomatic or cause hypoglycemia. Fructose - a monosaccharide which is present in high concentrations in fruit and honey, as well as part of the sucrose and sorbitol. deficiency of fructose-1-fosfataldolazy (aldolase B) With a lack of this enzyme develop the clinical syndrome of congenital fructose intolerance.Inheri...

December 20, 2016 00:03

Violation of pyruvate metabolism

Failure to metabolize pyruvate leads to lactic acidosis, and a variety of CNS disorders. Pyruvate - is an important substrate of carbohydrate metabolism. pyruvate dehydrogenase deficiency pyruvate dehydrogenase - a multienzyme complex responsible for the formation of pyruvate to acetyl Krebs cycle.Deficiency of this enzyme leads to increased pyruvate and hence increase the level of lact...

December 20, 2016 00:03

Periodic syndrome associated with receptors TNF ( TNF)

Family Irish fever (periodic syndrome associated with receptors of tumor necrosis factor (TNF)), - an inherited disease characterized by recurrent episodes of fever and myalgia migrating with painful erythema of the skin located above it.The level of TNF receptor type I low.Treatment for glucocorticosteroids and etanercept. periodic syndrome associated with TNF receptors has been described...

December 20, 2016 00:03

The use of melatonin in the oncology practice

Melatonin, a pineal gland hormone, has a powerful antioxidant, immunomodulating and detoxification effects.Studies in recent decades indicate that melatonin numerous onkostaticheskie inherent properties.Melatonin is involved in the modulation of cell cycle, induction of apoptosis, stimulation of cell differentiation, inhibition of metastasis.Hormone marked inhibitory effects against telomer...

November 28, 2016 00:10

Wasting

Wasting - alimentary-dependent condition caused by the predominant protein and / or energy starvation of sufficient duration and / or intensity.Protein-energy malnutrition appears complex disorders of homeostasis in the form of changes of metabolic processes, fluid and electrolyte imbalance, change in body composition, disorders of the nervous regulation of endocrine imbalance, immune syste...

November 28, 2016 00:10

Overweight and obesity in children

Currently, the terms "obesity in children" and "overweight" are equally often used in pediatrics, with the term "overweight" is more preferable. Obesity (Latin Adipositas, alimentary obesity.) - chronic eating disorder characterized by excessive accumulation of adipose tissue in the body. See also: Obesity - Information Browse codes in ICD-10 E65-E68.Obesity and other types of ...

November 27, 2016 00:18

Patau syndrome ( trisomy syndrome on chromosome 13 ) : causes, symptoms , diagnosis, treatment

Patau Syndrome (Trisomy 13 chromosome) develops in the presence of an extra 13th chromosome and contains defects of the forebrain development, face and eyes;expressed by mental retardation;low birth weight. Patau Syndrome (Trisomy 13 chromosome) occurs in about 1/10 000 live births;approximately 80% have the full trisomy 13. With age, the mother increases the likelihood of having a child w...

November 27, 2016 00:18

Diastolic left ventricular function in children with secondary cardiomyopathies

structure of cardiac pathology has undergone in the last decades of the last century significant changes.In Ukraine, there is a strong tendency to an increase in cardiovascular morbidity non-rheumatic nature, including - secondary cardiomyopathies (ILC).The prevalence of increased from 15.6% in 1994 to 27.79% in 2004 According to recommendations of the WHO working group of the Internation...